Modafinil Side effects


What are the Modafinil side effects you should know about of the drug.

Modafinil Administration

Before you begin using modafinil, and each time you obtain a refill, read the Medication Guide issued by your pharmacist. If you have any concerns, see your doctor or pharmacist.

Take this drug by mouth with or without food as advised by your doctor for narcolepsy, generally once daily in the morning. Alternatively, if directed by your doctor, the total daily amount of modafinil may be divided between a morning and a midday dose.

Take this drug by mouth with or without food as advised by your doctor for obstructive sleep apnea, generally once daily in the morning. Continue your other therapy (such as the CPAP machine or oral device) until your doctor instructs you otherwise.

If you’re using modafinil for shift work sleep problem, take it by mouth with or without food as advised by your doctor, generally once a day, one hour before your work shift begins.

The dosage is determined by your medical condition as well as your reaction to therapy. To get the most out of this drug, take it on a daily basis.

If you stop using this drug abruptly, you may have withdrawal symptoms (such as shaking, sweating, chills, nausea, vomiting, confusion). To assist avoid withdrawal, your doctor may gradually reduce your dose. If you have taken modafinil for a long period or in heavy dosages, you are more likely to have withdrawal symptoms. If you have withdrawal symptoms, contact your doctor or pharmacist straight away.

This drug may not function as effectively if used over an extended period of time. If this drug stops working properly, consult your doctor.

Despite the fact that it benefits many people, this medicine can occasionally lead to addiction. If you have a substance use issue (such as overuse or addiction to drugs/alcohol), your risk may be increased. To reduce the danger of addiction, take this medicine precisely as directed. For further information, see your doctor or pharmacist.

If your condition does not improve or worsens, notify your doctor.


Headache, nausea, agitation, dizziness, or difficulty sleeping are all possible side effects. Inform your doctor or pharmacist right once if any of these side effects continue or worsen.

Remember that your doctor has recommended this medicine because the benefit to you outweighs the risk of adverse effects. Many persons who use this drug have no major adverse effects.

Inform your doctor immediately away if you have any significant side effects, such as fast/pounding/irregular heartbeat or mental/mood problems (such as agitation, confusion, depression, hallucinations, rare thoughts of suicide).

If you have any really significant adverse effects, such as chest discomfort, get medical attention immediately.

It is uncommon for this medicine to cause a severe allergic response. However, get medical attention immediately if you detect any of the following signs of a severe allergic reaction: fever, enlarged lymph nodes, rash, itching/swelling (particularly of the face/tongue/throat), severe dizziness, or difficulty breathing.

This is not an exhaustive list of potential negative effects. Contact your doctor or pharmacist if you experience any other side effects not listed above.


Tell your doctor or pharmacist if you are allergic to modafinil or armodafinil, or if you have any additional allergies. Inactive chemicals in this product may cause allergic reactions or other complications. For further information, see your pharmacist.

Before using this medication, inform your doctor or pharmacist of your medical history, particularly of: heart problems (such as enlarged heart, mitral valve problem, chest pain, heart attack, irregular heartbeat), heart problems after taking stimulant drugs such as amphetamines (including chest pain, irregular heartbeat), high blood pressure, liver problems, mental/mood disorders (such as depression, mania, psychosis), and a personal or family history of a substance use disorder (suicide).

Sleep problems might impair your capacity to respond swiftly. Even if modafinil helps you stay awake, you may not be able to accomplish activities that demand rapid reflexes safely (such as driving). This medication may also cause dizziness. You may become dizzy if you consume alcohol or marijuana (cannabis). Do not drive, operate equipment, or do anything else that requires attentiveness until you are sure you can do it safely. Consume no alcoholic beverages. If you use marijuana, see your doctor (cannabis).

Inform your doctor or dentist about all of the products you consume before undergoing surgery (including prescription drugs, nonprescription drugs, and herbal products).

If you are pregnant or want to become pregnant, inform your doctor. You should avoid getting pregnant while using modafinil. Modafinil may be harmful to an unborn child. Inquire about non-hormonal birth control options while taking this drug and for two months after quitting it. If you become pregnant, immediately see your doctor about the risks and advantages of taking drug.

It is uncertain if this medication goes into breast milk. Before breast-feeding, consult your doctor.

Consult your pharmacist or doctor.


Drug interactions might alter the way your prescriptions operate or put you at risk for dangerous adverse effects. This guide does not include every conceivable medication interaction. Maintain a list of all the items you use (including prescription and nonprescription medicines, as well as herbal supplements) and discuss it with your doctor and pharmacist. Do not start, stop, or modify the dosage of any medications without first consulting your doctor.

Street drugs (such as methamphetamine and MDMA/”ecstasy”) may interact with this medication.

This medicine may reduce the efficacy of hormonal birth control methods such as tablets, patches, or rings. This might result in pregnancy. Consult your doctor or pharmacist about using extra reliable birth control methods while taking this medicine and for 1 month after quitting it. Inform your doctor if you see any new spotting or breakthrough bleeding, as these might indicate that your birth control isn’t functioning properly.

Modafinil might hasten the elimination of other drugs from your body, which may impair their effectiveness. Axitinib, bosutinib, and some medicines used to treat chronic hepatitis C (asunaprevir, ombitasvir/paritaprevir/ritonavir) are among the afflicted pharmaceuticals.

Some goods include substances that may cause your heart rate or blood pressure to rise. Inform your pharmacist about the products you’re using and inquire how to use them properly (especially cough-and-cold products or diet aids).

Caffeine might exacerbate the medication’s adverse effects. Avoid consuming significant amounts of caffeine-containing drinks (coffee, tea, and colas), eating big amounts of chocolate, and using caffeine-containing nonprescription items.

Armodafinil and modafinil are quite similar. Take no armodafinil-containing drugs while using modafinil.

Modafinil Side effects
Modafinil side effects


Call 911 if someone has overdosed and is experiencing significant symptoms like as passing out or difficulty breathing. Otherwise, contact a poison control centre immediately. Residents in the United States can contact their local poison control centre at 1-800-222-1222. Residents of Canada can contact a provincial poison control centre. Overdose symptoms include fast/irregular heartbeat, intense restlessness, and hallucinations.


Do not give this medicine to anybody else. It is illegal to share it.

Periodic laboratory and/or medical tests (such as blood pressure and heart rate) may be conducted to evaluate your progress or to look for negative effects. For further information, speak with your doctor.

Maintaining excellent sleep habits (such as sleeping in a dark/quiet room and avoiding coffee close to night) will help you sleep better if you have shift work sleep disorder.

Dose Omitted

If you forget to take a dosage, take it as soon as you recall. If the next dosage is approaching, skip the missing dose. Take your next dosage at your usual time. To catch up, do not increase the dose. Do not take missing doses close to night as this may make falling asleep more difficult.


Store away from light and moisture at room temperature. Keep out of the bathroom. Keep all drugs out of the reach of children and dogs.

Unless otherwise directed, do not flush drugs or pour them down the drain. When this product has expired or is no longer needed, properly dispose of it. Consult your pharmacist or a garbage disposal firm in your area.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

  1. Black, tarry stools
  2. blurred vision or other vision changes
  3. chest pain
  4. chills or fever
  5. clumsiness or unsteadiness
  6. confusion
  7. dizziness or fainting
  8. increased thirst and urination
  9. mental depression
  10. problems with memory
  11. rapidly changing moods
  12. shortness of breath
  13. sore throat
  14. trembling or shaking
  15. trouble in urinating
  16. uncontrolled movements of the face, mouth, or tongue
  17. unusual bleeding or bruising
  18. unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Agitation or excitement
  2. fast or pounding heartbeat
  3. increased blood pressure
  4. trouble with sleeping

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Anxiety
  2. headache
  3. nausea
  4. nervousness

Less common

  1. Back pain
  2. belching
  3. decrease in appetite
  4. diarrhea
  5. difficulty having a bowel movement
  6. dryness of the mouth
  7. dryness of the skin
  8. feeling of constant movement of self or surroundings
  9. flushing or redness of the skin
  10. heartburn
  11. indigestion
  12. muscle stiffness
  13. sores, ulcers, or white spots on the lips or in the mouth
  14. sour stomach
  15. stomach discomfort upset or pain
  16. stuffy or runny nose
  17. swelling
  18. tingling, burning, or prickling sensations in the skin
  19. vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Does this clear up your concern about Modafinil side effects?

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